MCAS
is a condition in which the individual experiences repeated episodes of the symptoms of anaphylaxis or allergic symptoms such as hives, swelling, low blood pressure, difficulty breathing and severe diarrhea. Primary symptoms include cardiovascular, dermatological, gastrointestinal, neurological and respiratory problems. High levels of mast cell mediators are released during those episodes. This can affect any and all of the body systems causing unexplained symptoms of inflammation with the absence of any microorganisms. The episodes respond to treatment with inhibitors or blockers of mast cell mediators.
Dermatological
- Flushing
- Hives
- Easy bruising
- Either a reddish or pale complection
- Itchiness
- Burning feeling
- Dermatographism
Cardiovascular
- Lightheadedneess, dizziness, presyncope, syncope, arrhythmia, tachycardia
Gastrointestinal
- Diarrhea and/or constipation, cramping, intestinal discomfort
- Nausea, vomiting, acid reflux
- Swallowing difficulties, throat tightness
Respiratory
- Congestion, coughing wheezing
Anaphylaxis:
- If to many mediators are released into a patient’s system, they
may also experience anaphylaxis, which primarily includes:
difficulty breathing, itchy hives, flushing or pale skin, feeling of
warmth, weak and rapid pulse, nausea, vomiting, diarrhea,
dizziness and fainting.